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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Vitamin E
Research Papers that Mention the Interaction
“A negative correlation between MDA and vitamin E, between MDA and GSH and a positive correlation between vitamin E and GSH was found.”
Vitamin E supplementation may ameliorate oxidative stress in type 1 diabetes mellitus patients.“ Vitamin E in erythrocytes had a significant correlation with the glutathione concentrations in the erythrocytes (r = 0.46, P<0.02).”
“ Vitamin E supplementation increased glutathione concentrations by 9% (P<0.01) and lowered concentrations of malondialdehyde by 23% (P<0.001) and of HbA1c by 16% (P<0.02) in erythrocytes of diabetic patients.”
“Recent evidence suggests that vitamin E enhances glutathione levels and may play a protective role in magnesium deficiency-induced cardiac lesions.”
“After supplementation with vitamin E there was a concomitant fall in erythrocyte superoxide dismutase (EC 1.15.1.1) activity (P < 0.001) and total glutathione concentration (P < 0.01).”
“Homocitrulline reduction of glutathione levels was completely prevented by melatonin and α‐tocopherol , whereas ornithine‐induced decrease of glutathione levels was only attenuated by these free radical scavengers.”
“Numerous in vitro experiments demonstrate antioxidant synergism between alpha-tocopherol and ascorbate, reduced glutathione , NADPH, and cellular electron transport proteins.”
“NG and α-TOC administered singularly or combined in the PC-3 cell line, affected the activity of several enzymes biomarkers of the cellular antioxidant activity, as well as the concentration of total glutathione (GSH + GSSG) and thiobarbituric acid reactive substances (TBARS).”
“Co-… and vitamin E significantly increased total antioxidant capacity (mg/dl) (1.15 ± 0.93 vs -0.6 ± 0.72; … activity (IU/L) (1.19 ± 1.06 vs 0.12 ± 0.36; P < 0.001) and glutathione levels (μmol/L) (1.5 ± 1.06 … ± 1.43; P = 0.028).”
“Co-treatment with curcumin or α-tocopherol significantly attenuates depleted GSH , decrease in MDA and 8-OH-dG levels in propoxur exposed cells (p < 0.05).”
“Supplementation with lutein, zeaxanthin, or α-tocopherol increased GSH levels and GSH:GSSG ratio, particularly in response to oxidative stress.”
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