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Last Updated: 3 years ago

Possible Interaction: Glutathione and Vinblastine

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supplement:

Glutathione

drug:

Vinblastine

Research Papers that Mention the Interaction

“We also show that GSH export in MDCKII-MRP2 cells increases in the presence of vinblastine , and that the stochiometry between drug and GSH exported is between two and three.”

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

British Journal of Cancer • 2000 | View Paper

“Taxol, VP-16, vincristine, and vinblastine were also poor inhibitors of LTC4 transport but inhibition by these compounds was enhanced by GSH.”

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport.

The Journal of biological chemistry • 1996 | View Paper

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