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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Trehalose
Research Papers that Mention the Interaction
“ Trehalose application also increased CHIP and HSP70 expression and GSH free radical levels.”
Trehalose Improves Human Fibroblast Deficits in a New CHIP-Mutation Related Ataxia“Further studies have shown that trehalose activates the expressions of downstream target genes HO-1, NQO1, SOD, GSH and CAT by promoting the nuclear translocation of Nrf2 in the liver.”
Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability.“Moreover, Cd‐activated Nrf2 target genes, including phase II detoxifying enzymes, that is, NAD(… heme oxygenase‐1, direct antioxidant proteins, that is, glutathione peroxidase, superoxide dismutase, catalase, and glutathione biosynthesis‐related proteins, that is, glutamatecysteine ligase catalytic subunit, glutamate … glutathione reductase, were all downregulated by co‐treatment with Tre.”
“Compared with the other groups, trehalose at the concentration of 25 and 50 mM increased GSH activity (P < 0.05).”
“The application of 200 mM trehalose produced the least amount of GSH activity among all of the groups (P < 0.05).”
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