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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutathione and Tamoxifen

supplement:

Glutathione

Research Papers that Mention the Interaction

Cysteine and glutathione inhibited the binding of TXF without significantly affecting P-450-mediated metabolism of TXF, possibly by reacting with txf* or by competing for the same binding sites.
Cancer research  •  1991  |  View Paper
TAM also inhibited the calcium-induced release of matrix glutathione.
Toxicology and applied pharmacology  •  1998  |  View Paper
Additionally, ascorbic acid and glutathione , inhibitors of covalent binding of tamoxifen , produced an elevation of methylated catechol.
Cancer research  •  1996  |  View Paper
Sequential observations showed an increased incidence of glutathione S-transferase-positive foci of hepatocellular alteration by 3 months with tamoxifen in the absence of hepatotoxicity, with the first liver carcinoma appearing by 6 months of treatment.
Cancer research  •  1993  |  View Paper