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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Tacrolimus

supplement:

Glutathione

Research Papers that Mention the Interaction

Additionally, tacrolimus dose-adjusted trough concentrations positively correlated with GFR and negatively with GPX and GSH.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2015  |  View Paper
Tacrolimus has been shown to induce cholestasis by inhibiting biliary excretion of glutathione [2].
Transplant international : official journal of the European Society for Organ Transplantation  •  2012  |  View Paper
Tacrolimus significantly decreased GSH level and catalase activity while increasing MDA level.
BioMed research international  •  2014  |  View Paper
These findings suggest that tacrolimus impacts post-ischemic GSH metabolism when administered as a rinse solution for liver allografts through an unknown pathway.
The Journal of surgical research  •  2012  |  View Paper