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Discover Supplement-Drug Interactions

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Last Updated: 5 days ago

Possible Interaction: Glutathione and Sodium Stibogluconate

Research Papers that Mention the Interaction

Consistent with the proposed mechanism from in vitro …, increasing tissue GSH levels in the presence of SSG by cotreatment of L. donovani-… mice with SSG solution and GSH incorporated into nonionic surfactant vesicles was more effective in reducing liver, spleen, and bone marrow parasite burdens than monotherapy with SSG.
Antimicrobial Agents and Chemotherapy  •  2006  |  View Paper
Measurement of glutathione levels in the spleens and livers of treated mice showed that the ability of the combined therapy to inhibit glutathione levels was also dependent on the SSG dose used and that the combined treatment exhibited organ-dependent effects.
Antimicrobial Agents and Chemotherapy  •  2003  |  View Paper
Pentostam , a Sb(V)-containing drug that is one of the first-line therapeutic agents for treatment of leishmaniasis, inhibited uptake after reaction with GSH.
Proceedings of the National Academy of Sciences of the United States of America  •  1996  |  View Paper