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Last Updated: 2 years ago

Possible Interaction: Glutathione and Sodium Selenite

supplement:

Glutathione

supplement:

Sodium Selenite

Research Papers that Mention the Interaction

It was demonstrated that incubation of blood platelets with sodium selenite (1-100 microM) resulted in a dose- and time-dependent loss of platelet thiols (both glutathione and protein -SH groups).
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  1999  |  View Paper
Sodium selenite concentrations of 0.1 mM also decreased the intracellular glutathione concentration of target cells during an oxidant stress, and reducing target cell glutathione concentrations with buthionine sulfoximine increased their sensitivity to oxygen-related chromosomal damage.
The Journal of clinical investigation  •  1985  |  View Paper
Glutathione strongly enhanced the induction of unscheduled DNA synthesis (UDS) in cultured human cells by inorganic selenium compounds: sodium selenate, sodium selenite and sodium selenide.
Mutation research  •  1980  |  View Paper
The antioxidants, vitamin C and sodium selenite , directly increased GSH content while diminishing ROS formation and DNA damage in H. pylori-infected SGC-7901 cells, indicating that vitamin C and sodium selenite can protect gastric cells against H. pylori damage.
Die Pharmazie  •  2006  |  View Paper
Addition of sodium selenite to human red cells, under ATP deplete conditions, induces a rapid oxidation of both glutathione and protein sulphydryl groups.
Biochimica et biophysica acta  •  1994  |  View Paper
SS treatment significantly increased the glutathione level and decreased high malondialdehyde level in tissues of the SS+4-NP group as compared with 4-NP group.
Biological trace element research  •  2020  |  View Paper
In addition, sodium selenite injection caused reduced antioxidant enzymes (superoxide dismutase (SOD) and glutathione peroxidase (GPx)), glutathione ( GSH ) depletion, and malondialdehyde (MDA) production in the lens.
Molecular vision  •  2019  |  View Paper
Sodium selenite supplementation markedly reduced total bilirubin and ALT activity and restored the antioxidant enzymes (SOD and GSH ) and MDA and catalase activity.
Pakistan journal of pharmaceutical sciences  •  2013  |  View Paper
Sodium selenite significantly reversed the oxidative stress effects of radiation that was evidenced by increasing in lipid peroxide level and decreasing in glutathione level, and glutathione peroxidase (GPx) activity.
PloS one  •  2012  |  View Paper
Sodium selenite , L-selenocystine, L-selenomethionine, and Se-methyl-L-selenocysteine all enhanced glutathione S-transferase activity.
Toxicology  •  2006  |  View Paper
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