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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Selegiline
Research Papers that Mention the Interaction
“In macrophage cultures, glutathione (GSH) was upregulated strongly after treatment with dopamine, morphine or selegiline , and this effect was enhanced when cells were pre-exposed to virus.”
Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.“The two higher dose levels of selegiline (5 and 10 mg/kg) significantly increased locomotor activity, improved prepulse inhibition (PPI), reduced striatal and cortical lipid peroxidation, caspase-3, and Bax, and increased GSH level, catalase, and superoxide dismutase activities and Bcl2 expression.”
Antioxidant and antiapoptotic actions of selegiline protect against 3-NP-induced neurotoxicity in rats“Moreover, selegiline significantly increased glutathione level.”
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