“1) MeHg induced Hg accumulation, pathological injury, and apoptosis …, 8-OHdG, MDA, and carbonyl, and inhibited sulfydryl and GSH ; (3) MeHg elevated Glu, decreased Gln, and … mRNA expression and protein levels; (4) riluzole antagonized MeHg-induced downregulation of GLAST and GLT-… depletion, oxidative stress, pathological injury, and apoptosis obviously.”
“Data indicate that MeHg administration induced oxidative stress in cortex and that riluzole could antagonize this situation through elevation of GSH synthesis by activating of GluTs.”