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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
Research Papers that Mention the Interaction
“We studied the capacity of different antioxidants (ascorbic acid, alpha-tocopherol, pyrrolidine dithiocarbamate, N-acetylcysteine, and glutathione ) to block the increase in tyrosine phosphorylation in human monocytes seen after stimulation with strong contact sensitizers.”
Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers.“A correlation was observed between sensitizing status and the ability to perturb glutathione status , to induce glutathione S-transferase activity, and to stimulate NAD(P)H utilization.”
Perturbation of glutathione status and generation of oxidative stress in mouse skin following application of contact allergenic sesquiterpene lactones and isothiocyanates.“Thus, although all three sensitizers reduce glutathione levels, they have different effects on cellular morphology and hence such secondary effects may account for the different degrees of radiation sensitization seen with these agents.”
“Incubation of hepatocytes with 5 mM radiosensitizers led to a decrease in the intracellular GSH level.”
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