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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
Research Papers that Mention the Interaction
“Coincubation of IPO and rabbit CYP4B1 with glutathione gave rise to multiple products due likely to the presence of both sulfur and nitrogen nucleophiles in the same trapping molecule.”
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.“In conclusion, glutathione metabolic status is altered in the aged rabbit aorta reflecting depressed &ggr;‐GCS‐ and &ggr;‐GT‐related GSH biosynthesis and GSSG burden eventually favoring vascular oxidative stress and dysfunction.”
Glutathione metabolic status in the aged rabbit aorta“We have found that GSH inhibits purified lactate dehydrogenase (1.56 U LDH/ml) from rabbit skeletal muscle after 6 min pre-incubation with an ED50 of about 5.4 microM. The inhibition is time dependent with a maximum after 45 minutes pre-incubation.”
“Our data suggest a modulatory role of glutathione in the release and/or clearance of the components of the fibrinolytic system in the rabbit.”
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