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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Quercetin
Research Papers that Mention the Interaction
“We also observed that the expression of oxidative stress markers, such as lipid peroxide (LPO), nitric oxide (NO), superoxide dismutase (SOD), glucose-6-phosphate (G6PD), and glutathione (GSH), could be reduced by quercetin , suggesting that the anti-inflammatory function of quercetin comes from its antioxidant effect.”
Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice“ Quercetin treatment significantly augmented SOD, GSH , catalase and 5 HT levels.”
“Adding glutathione to the detergent-based assay, as used in these studies to measure furin processing activity, strongly reduced inhibition by a number of polyphenols (catechins, gallic acid and quercetin ), while the effect on the genuine inhibitor nona-D-arginine remained unchanged.”
“Our results suggest that glutathionylation of quercetin occurs in both murine hepatic suspensions and humans and indicate that under certain conditions, quercetin intermediates require inactivation through conjugation with glutathione.”
“Total levels of oxidative stress markers were profoundly decreased and the activity of GSH was increased by quercetin (P < 0.05).”
“Our results indicated that Que significantly increased cell viability, superoxide dismutase, and GSH levels, while decreased alanine aminotransferase/aspartate aminotransferase levels.”
“ Quercetin also increased GSH content, mRNA levels of glutamylcysteine-synthetase (GCS) and expression and/or activity of glutathione-peroxidase, glutathione-reductase and GCS after 4h of incubation, and glutathione-S-transferase after 18h of exposure.”
“The present study shows that the oxidation products of both monoHER and quercetin are reactive towards thiol groups of both GSH and proteins.”
“ Quercetin , partially prevented the GSH decrease and the formation of HB, but did not prevent MetHb formation from oxidative damage by tBHP.”
“It is concluded that GSH depletion explains at least in part the selective potentiation of ATO toxicity by quercetin , and that this flavonoid might be used to increase the clinical efficacy of the antileukemic drug.”
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