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Last Updated: a month ago

Possible Interaction: Glutathione and Propyl Gallate

Research Papers that Mention the Interaction

In conclusion, PG induced growth inhibition and death of ECs, especially CPAEC via GSH depletion.
PG also dose-dependently increased GSH depleted cells in both ECs.
Toxicology in vitro : an international journal published in association with BIBRA  •  2010  |  View Paper
Furthermore, PG increased the GSH depleted cell number and decreased GSH level in CPAEC.
International journal of molecular medicine  •  2010  |  View Paper
PG also increased GSH depleted cell numbers in HeLa cells.
Molecular Biology Reports  •  2010  |  View Paper
PG significantly increased GSH depleted cells in a time- and dose-dependent manner.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2009  |  View Paper
PG depleted intracellular GSH content in HeLa cells at 24 h. Treatment with caspase inhibitor reduced ROS levels and significantly prevented GSH depletion in PG-treated HeLa cells at 24 h. In conclusion, PG induced apoptosis in HeLa cells.
Archives of Toxicology  •  2009  |  View Paper
In whole body homogenates, propyl gallate (PG; 25 micrograms/ml) increased the glutathione content significantly up to the 22nd day of life whereas in mitochondria it increased during all age intervals in the two sexes with the exception of the 36th and 43rd day of survival in males.
Gerontology  •  1992  |  View Paper
Moreover, a marked inhibition of G-6-Pase activity was found also when propyl gallate and reduced glutathione were added, at different concentrations, to incubation mixture.
Bollettino della Societa italiana di biologia sperimentale  •  1979  |  View Paper
PG increased ROS levels and caused GSH depletion in both cell lines at 24 h. MAPK inhibitors increased O2•- levels and GSH depletion in PG-treated Calu-6 cells, and JNK and p38 inhibitors increased ROS levels and GSH depletion in PG-treated A549 cells.
Toxicology in vitro : an international journal published in association with BIBRA  •  2021  |  View Paper
In conclusion, PG inhibited the growth of CPAECs by regulating GSH levels.
Molecular medicine reports  •  2009  |  View Paper