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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Proline
Research Papers that Mention the Interaction
“Reduced glutathione demonstrated a more short-lived reduction after G2 in PRO compared to PLA.”
Post-Game High Protein Intake May Improve Recovery of Football-Specific Performance during a Congested Game Fixture: Results from the PRO-FOOTBALL Study“Of note, proline resulted in lower reactive oxygen species (ROS) level, upregulated mRNA expression of the catalytic subunit of glutamate–cysteine ligase (GCLC) and glutathione synthetase (GSS), as well as enhanced total (T)-GSH and GSH concentration when compared with a control.”
L-Proline Activates Mammalian Target of Rapamycin Complex 1 and Modulates Redox Environment in Porcine Trophectoderm Cells“ PDC decreased intracellular glutamate accumulation and exacerbated glutathione depletion in the presence of glutamate.”
“… proline … GSH and AsA content, maintenance of a high GSH/GSSG ratio and increased the activities of APX, DHAR, MDHAR, GR, GST, GPX, CAT, Gly I … as compared to the control and mostly also Cd-stressed plants, with a concomitant decrease in GSSG content, H2O2 and lipid peroxidation level.”
Up-regulation of antioxidant and glyoxalase systems by exogenous glycinebetaine and proline in mung bean confer tolerance to cadmium stress“Levels of ASC and GSH in BY-2 cells under salt stress were lower in the presence of proline or betaine than in the absence of proline or betaine whereas there was no difference in redox status.”
“The observed protonation of adsorbed l-glutathione upon interaction with proline goes along with a structural change of the former, which seems to play an important role for enantiodiscrimination.”
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