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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Probucol
Research Papers that Mention the Interaction
“In silico studies with GPx1 pointed to a potential binding site for probucol at the close vicinity of the GSH pocket.”
Probucol Protects Neuronal Cells Against Peroxide-Induced Damage and Directly Activates Glutathione Peroxidase-1“The levels of …, SOD and GSH in probucol group were higher than those in control group [(80±27) vs (72±26) ml·min(-1)·1.73 m(-2,) (67±9) vs (58±8)U/ml, (4.6±0.9) vs (3.9±0.8)U/ml, P<0.05].”
“Reduced glutathione , urate, and Probucol were ineffective.”
“Only PROB caused significant improvement in GSH and normalized GSSG levels.”
Modulation of adriamycin-induced changes in serum free fatty acids, albumin and cardiac oxidative stress“Renal cortex from obstructed rats treated with probucol had significantly higher levels of reduced glutathione than kidneys of obstructed rats not given probucol.”
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