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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
drug:
Prednisolone
Research Papers that Mention the Interaction
“There was a statistically significant positive correlation between GSH levels and in vitro sensitivity to daunorubicin (Spearman's rank correlation coefficient rs = 0.38, p < 0.04), melphalan (rs = 0.39, p < 0.04) and prednisolone (rs = 0.48, p < 0.01), but not mitozantrone, etoposide or 6-thioguanine.”
Raised intracellular glutathione levels correlate with in vitro resistance to cytotoxic drugs in leukaemic cells from patients with acute lymphoblastic leukemia.“The present results indicate that prednisolone increases the capacity to replete depleted hepatic glutathione stores in mice.”
Prednisolone stimulates hepatic glutathione synthesis in mice. Protection by prednisolone against acetaminophen hepatotoxicity in vivo.
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