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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Oxytocin
Research Papers that Mention the Interaction
“Similarly, OT was more rapidly degraded in human kidney microvilli membranes in the presence of glutathione than in the human crude liver homogenate, when using equal amounts of protein in the incubations.”
“The metabolization of the oxytocin analogue, antocin, also varied with the presence of glutathione.”
Metabolism of vasopressin, oxytocin and their analogues [Mpa1, d-Arg8]-vasopressin (dDAVP) and [Mpa1, d-Tyr(Et)2, Thr4, Orn8]-oxytocin (antocin) in human kidney and liver homogenates“Besides, OT significantly reduced plasma lipid peroxides (p < 0.05) and increased glutathione levels in diabetic rats (p < 0.001).”
Oxytocin provides protection against diabetic polyneuropathy in rats“SOD activity and GSH levels were increased in Kisspeptin and/or OXY applied I/R group compared to I/R group.”
“Administration of OT significantly decreased the gene expression of both NADPH oxidase and P38 MAPK, nitric oxide (NO), myloperoxidase (MPO), and TBARS, furthermore it increased the renal tissue levels of antioxidants; reduced glutathione (GSH), and superoxide dismutase (SOD).”
“Lower GSH levels following Oxytocin augmentation indicate an oxidative stress, though selected measures of oxidative stress demonstrate no cell damage.”
Labor Augmentation with Oxytocin Decreases Glutathione Level“Thereby, glutathione can act as a nucleophile with oxytocin forming four new conjugates via a disulphide bondage.”
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