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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Oxypurinol
Research Papers that Mention the Interaction
“Hypoxia induced GSH efflux and cytotoxicity were also prevented by oxypurinol , a xanthine oxidase inhibitor, as well as by the polyphenolic antioxidant quercetin, suggesting that reactive oxygen species contributed to the GSH efflux and cell lysis.”
Rapid and specific efflux of glutathione before hepatocyte injury induced by hypoxia.“… GSH decrease and TBA-RS increase in … of viability loss in presence of oxipurinol in contrast to lacking improvement of ATP and GTP restoration by this drug speak in favor for the … major causal component for postischemic injury of hepatocytes in comparison with depletion of energy-rich purine nucleotides.”
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