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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Glutathione and Nifurtimox

supplement:

Glutathione

Research Papers that Mention the Interaction

We have previously shown that glutathione synthesis inhibition increases nifurtimox and benznidazole activity.
Biological research  •  2010  |  View Paper
Addition of GSH or free-radical scavengers (catalase, superoxide dismutase, mannitol, sodium benzoate or L-histidine) prevented the effect of nifurtimox on lipid peroxidation reactions.
Biochemical pharmacology  •  1984  |  View Paper
Treatment of rats with nifurtimox , a nitrofuran derivative widely used for the treatment of Chagas' disease, induced a time- and dose-dependent depletion of liver glutathione , maximal effects being obtained with 200 mg nifurtimox/kg body weight.
Biochemical pharmacology  •  1983  |  View Paper