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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutathione and Nerve Growth Factor

Research Papers that Mention the Interaction

We present evidence that this inhibition is mediated by the rapid activation of glutathione redox cycling by NGF.
The Journal of Neuroscience  •  2007  |  View Paper
NGF was also shown to upregulate glutathione in DRG neurons.
Neurotoxicology  •  2005  |  View Paper
NGF prevented both the loss of viability seen after 24 hours amyloid beta treatment and also protected glutathione levels.
BioFactors  •  2003  |  View Paper
The increased GSH and L-cysteine concentrations by NGF also served as intracellular antioxidants.
Brain research  •  1996  |  View Paper
Treatment with NGF or forskolin for 24 h increased the level of cellular antioxidant glutathione ( GSH ) by 1.6-2.0-fold.
Neuroscience Letters  •  1996  |  View Paper
NGF increased catalase and GSH Px mRNA levels in PC 12 cells in a time‐ and dose‐dependent manner.
Journal of neurochemistry  •  1994  |  View Paper
NGF stimulated GSH peroxidase by 30% after 3 days and glucose 6‐phosphate dehydroge‐nase by 50% after 2 days.
Specifically, NGF increased γ‐glutamylcysteine synthetase (GCS) activity, the rate‐limiting enzyme for GSH synthesis, by 50% after 9h and GSH levels by 100% after 24 h of treatment.
Journal of neurochemistry  •  1993  |  View Paper