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Last Updated: 2 years ago

Possible Interaction: Glutathione and Myricetin





Research Papers that Mention the Interaction

Recently, it has been shown that fraxetin (coumarin) and myricetin (flavonoid) have significant neuroprotective effects against apoptosis induced by rotenone, increase the total glutathione levels in vitro, and inhibit lipid peroxidation.
Toxicology and applied pharmacology  •  2005  |  View Paper
Myricetin significantly reduced oxidative stress through decreasing MDA level and increasing the levels of SOD and GSH in the intestinal tissues compared with I/R control rats.
Pharmacological research  •  2018  |  View Paper
Results: Apigenin, myricetin and their combination significantly reduced blood BUN, serum Cr, caspase-3TNF-α, IL-6, COXI and COXII, MDA levels and significantly increased GSH level and catalase activity parallel to, histopathological improvement in kidney tissues.
Pharmaceutical biology  •  2017  |  View Paper
Topical treatment with all three doses of E‐AP‐SM2001 and 5 nm myricetin attenuated the UV‐induced depletion of GSH , activation of MMPs, production of IL‐1β, the decrease in IL‐10 and keratinocyte apoptosis.
Basic & clinical pharmacology & toxicology  •  2015  |  View Paper
Further the anti oxidant enzymes like Catalase, Glutathione peroxidase and GSH were significantly rejuvenated following myricetin supplementation in a dose dependent manner.
Journal of experimental therapeutics & oncology  •  2011  |  View Paper
Myricetin inhibited TNF-alpha-induced MKK4 activity and bound glutathione S-transferase-MKK4 directly by competing with ATP.
Biochemical pharmacology  •  2009  |  View Paper
Myricetin pretreatment reduced the level of malondialdehyde (MDA) and increased that of total glutathione (GSSG/GSH) and superoxide dismutase (SOD) in gastric tissues.
Evidence-based complementary and alternative medicine : eCAM  •  2021  |  View Paper
Treatment of the H2O2-stressed epithelial cells with myricetin caused significant (P<0.05) increased levels of SOD, CAT, and GSH.
Medical science monitor : international medical journal of experimental and clinical research  •  2020  |  View Paper
Moreover, myricetin completely blocked MeHg-induced ROS formation and lipid peroxidation and partially prevented MeHg-induced GSH depletion.
Environmental toxicology and pharmacology  •  2010  |  View Paper