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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Montelukast
Research Papers that Mention the Interaction
“ Montelukast significantly reduced JNK level and NFκB p65 expression, and inhibited proinflammatory cytokines (TNF-α and IL-6) as well as oxidative stress (MDA, NO, and GSH).”
Montelukast ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting TNF-α/JNK signaling pathway.“The inhibitory effect of montelukast was diminished by treatment with S‐hexyl GSH , whereas the effect of BayCysLT2RA was enhanced with increasing dose of S‐hexyl GSH.”
“The GSH levels in renal tissue of only GEN-treated rats were significantly lower than those in control group, and administration of MK to GEN-treated rats significantly increased the level of GSH.”
“In contrast, ML prevents these effects of CP through cause an increase in GSH , CAT, GPx, and SOD levels and a decrease in formation of TBARS.”
“The glutathione levels and superoxide dismutase activity were significantly increased in the lung, liver, and kidney tissues after MLK treatment.”
“Tissue malondialdehyde levels and glutathione consumptions also decreased significantly in the I/R+montelukast and I/R+MK-886 groups compared with the I/R group.”
“Similarly, the significant decrease in tissue glutathione level in the I/R group compared with controls was also prevented by montelukast.”
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