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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Masoprocol
Research Papers that Mention the Interaction
“Furthermore, NDGA significantly blocked RTV-induced increase of superoxide anion in the PA rings and inhibited RTV-induced decrease of glutathione in HPAECs.”
Nordihydroguaiaretic acid (NDGA) inhibits ritonavir-induced endothelial dysfunction in porcine pulmonary arteries“This was supported by the findings that glutathione disulfide levels were increased by 4 h following treatment with 10 microM NDGA , that pretreatment with N-acetylcysteine completely blocked the NDGA-induced loss of membrane potential and apoptosis, and that lipid peroxidation was enhanced in cells treated with NDGA.”
“Sulfhydryl compounds, GSH and cysteine, prevented the inhibition of succinoxidase activity by NDGA.”
“Mel-induced GSH depletion was correlated with its neurotoxicity as the two powerful protective agents of monohalomethane toxicity, 3-amino-1-[m-(trifluoromethyl) phenyl]-2-pyrazoline (BW 755C, 1 mM) and nordihydroguaiaretic acid (NDGA, 10 microM) provided a 20-fold protection against depletion of GSH levels following Mel exposure.”
“This effect of GSH was blocked by pretreatment with nordihydroguiaretic acid (30 microM), an inhibitor of 5-lipoxygenase.”
“ NDGA treatment also restored reduced glutathione level and activities of antioxidant enzymes.”
Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin
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