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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Lutein
Research Papers that Mention the Interaction
“Supplementation with lutein , zeaxanthin, or α-tocopherol increased GSH levels and GSH:GSSG ratio, particularly in response to oxidative stress.”
Lutein and zeaxanthin supplementation reduces H2O2-induced oxidative damage in human lens epithelial cells“The oral administration of lutein in mice for 1 month significantly increased the activity of catalase, superoxide dismutase, glutathione reductase and glutathione in blood and liver while the activity of glutathione peroxidase and glutathione-S-transferase were found to be increased in the liver tissue.”
Antioxidant activity of carotenoid lutein in vitro and in vivo.“No differences were observed in CAT levels, and LT treatment increased GSH levels compared with a negative control group, reinforcing the role of this carotenoid as an antioxidant.”
“ LU pretreatment also enhanced cardiac thioredoxin (Trx) and glutathione (GSH) contents as well as reduced lipid peroxidation, compared to the untreated group.”
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway.“Moreover, lutein decreased the malondialdehyde content, increased the oxygen radical absorbance capacity level, glutathione , the vitamin C contents and total superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities.”
“With increasing levels of lycopene and lutein the consumption of encapsulated GSH decreased moderately, and high levels of β-carotene led to a more pronounced loss of GSH.”
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