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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Lovastatin

supplement:

Glutathione

Research Papers that Mention the Interaction

All four lung cancer cell lines had a decrease in glutathione after lovastatin treatment consistent with reduced protection against reactive oxidant species.
Lung  •  2007  |  View Paper
Lovastatin similarly increased SOD, CAT and GSH by 32%, 29%, and 64% in the liver and by 17%, 26%, and 73% in the kidney of alloxan‐treated rats.
Fundamental & clinical pharmacology  •  2007  |  View Paper
Conclusion: Lovastatin has an inhibitory effect on tumor cell growth, probably as a result of the regulation of glutathione , and it may be involved with autophagy, apoptosis and changes in resistance to antineoplastic agents.
The journal of obstetrics and gynaecology research  •  2016  |  View Paper