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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Linoleic Acid
Research Papers that Mention the Interaction
“The photohemolysis rate and photoperoxidation of linoleic acid were inhibited significantly by reduced glutathione.”
Photosensitizing properties of Actarit, an antirheumatic drug.“In control cells, treatment with linoleic acid reduced intracellular glutathione levels and induced the DNA binding activity of nuclear factor-kappaB (NF-kappaB) leading to the upregulation of interleukin-6 (IL-6).”
Cholesterol attenuates linoleic acid-induced endothelial cell activation.“In vitro beta-hematin formation promoted by Plasmodium yoelii homogenate, the lipid extracts, and linoleic acid were blocked by ascorbic acid, reduced glutathione , sodium dithionite, beta-mercaptoethanol, dithiothreitol, and superoxide dismutase.”
“Kinetic and mass spectrometric analyses reveal that nitroalkene derivatives of oleic acid (OA-NO2) and linoleic acid (LNO2) rapidly react with GSH and Cys via Michael addition reaction.”
Nitro-fatty Acid Reaction with Glutathione and Cysteine“During … LA with these homogenates … presence of glutathione –glutathione peroxidase (GSH–GPx), which can reduce hydroperoxy fatty acids to the corresponding hydroxy acids, the formation of (R)-1-octen-… was significantly inhibited, whereas the amount of 10-hydroxy-(8E,12Z)-8,12-octadecadienoic acid (10-HODE) was significantly increased.”
“The induced photoperoxidation of linoleic acid was inhibited significantly by sodium azide and reduced gluthathione.”
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