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“Furthermore, sperm ROS levels decreased while GSH and mitochondrial activity levels increased in 5 mM LC group compared to those in the untreated group (P < 0.01).”
“The presence of L-carnitine also prevented the decrease of low-molecular-weight thiols ( glutathione , cysteine, and homocysteine) in plasma caused by peroxynitrite and protected plasma lipids against peroxidation induced by peroxynitrite.”
“Furthermore, after LC treatment, the level of intracellular reactive oxygen species in aged oocytes significantly decreased, and glutathione levels significantly increased, compared to those in untreated aged oocytes.”
The Journal of reproduction and development • 2019 | View Paper
“NO was significantly decreased, while renal glutathione and cytochrome p450 were significantly increased in groups treated with l-carnitine or cimetidine as compared to group II.”
“ L-carnitine treatment did not improve the nuclear maturation of oocytes but significantly increased intracellular GSH levels, which led to a reduction of reactive oxygen species (ROS) levels in IVM oocytes.”
“Adding 0.5 mg/mL of L-carnitine during IVM also significantly reduced intracellular reactive oxygen species (ROS), and increased glutathione (GSH) concentrations.”
“ L-carnitine significantly decreased (p <0.05) the levels of the MDA and CP and significantly increased (p <0.05) the serum antioxidant capacity: glutathione and DHA.”
Pediatric endocrinology, diabetes, and metabolism • 2010 | View Paper
“Administration of L-carnitine significantly reduced AA-induced elevations in AST, ALT, TSA and MDA concentrations and increased GSH levels at all sampling points.”