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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Levetiracetam
Research Papers that Mention the Interaction
“ GSH and SOD activity were significantly reduced by valproate and levetiracetam treatment.”
Effect of lamotrigine, levetiracetam & topiramate on neurobehavioural parameters & oxidative stress in comparison with valproate in rats“Furthermore, LEV significantly decreased lipid peroxide levels, a marker of lipid peroxidation, and induced glutathione levels , catalase and superoxide dismutase activity in PD rats compared with saline group.”
“… LVT decreased significantly MDA in the cortex (KA + vehicle = 0.25 +/- 0.03 nmol/mg … +/- 0,08 nmol/mg protein; P < 0.005), prevented the brain loss of GSH in both cortex (KA + vehicle = 5 +/- 1 micromol/g protein; ….05), reduced brain IL-1beta mRNA and markedly controlled seizures.”
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