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Last Updated: 2 years ago

Possible Interaction: Glutathione and Ketamine

supplement:

Glutathione

Research Papers that Mention the Interaction

In addition, ketamine treatment caused significant glutathione depletion, lipid peroxidation and reduction in catalase activity.
Life sciences  •  2020  |  View Paper
ketamine administration increased MDA ( p < 0.001), TNF-α ( p < 0.01), IL-6 ( p < 0.01), COX-2 ( … TnI ( p < 0.001), CK-MB ( p < 0.001) and CK ( p < 0.01) levels whereas decreased GSH ( p < 0.05) and Nrf-2 ( … CAT ( p < 0.05) enzyme activities.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2020  |  View Paper
The study demonstrated that, in the uterine and … tissues of rats that have been administered ketamine , there was a decrease in the levels of total glutathione and superoxide dismutase, while malondialdehyde and myeloperoxidase was increased: however it was observed that these ratios were reversed in the ketamine+nimesulide group.
General physiology and biophysics  •  2019  |  View Paper
In addition, the administration of KET decreased GSH and increased nitrite, lipid peroxidation and myeloperoxidase activity.
Neuroscience  •  2018  |  View Paper
Morin alone or in combination with ketamine significantly increased glutathione concentration, superoxide dismutase and catalase activities compared with saline- or ketamine-treated mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2018  |  View Paper
Ketamine inhibited chemical- or ischemia-induced lipid peroxidation as well as ischemic glutathione depletion.
Neuroscience  •  1991  |  View Paper
Furthermore, ketamine treatment increased the urination rate (P<0.05), pathological score (P<0.05), levels of the oxidative stress product malondialdehyde (P<0.05) in addition to reducing the expression of the anti-oxidative stress enzyme superoxide dismutase (P<0.05) and glutathione-SH (P<0.05).
Experimental and therapeutic medicine  •  2020  |  View Paper