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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Isoflurane
Research Papers that Mention the Interaction
“Conclusion Treatment with isoflurane or propofol may enhance GSH production by facilitating translocation of Nrf2 into the nucleus and increasing EAAC1mRNA expression in the rat hippocampus.”
Effects of propofol and isoflurane on excitatory amino acid carrier 1 mRNA and glutathione protein levels in rat hippocampus“ ISO increased the production of NADPH and glutathione ( GSH ), and scavenged reactive oxygen species (ROS), while TIGAR knockdown decreased GSH and NADPH production and increased the level of ROS.”
“Exposure to halothane and to isoflurane , but not to enflurane, further decreased the glutathione level.”
“The significant increases in alpha glutathione S‐transferase concentrations in patients receiving isoflurane suggest a transient disturbance of hepatocellular function.”
Comparison of the effects of desflurane and isoflurane anaesthesia on hepatocellular function assessed by alpha glutathione S‐transferase
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