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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Interferons

supplement:

Glutathione

Research Papers that Mention the Interaction

Wang et al. demonstrate that IFNγ downregulates both system xc subunits (SLC3A2 and SLC7A11) at the transcriptional level, thereby causing depletion of the intracellular GSH pool and triggering ferroptosis in cancer cells.
Cell Research  •  2019  |  View Paper
These results indicate that GSH induces MMP‐2 and MMP‐1 expression in normal HHF and that GSH reduces MMP‐2 and MMP‐1 in transformed fibroblast cells.
Journal of cellular biochemistry  •  1996  |  View Paper
More importantly, the probe revealed that NO induced by interferon-γ (IFN-γ), lipopolysaccharide (LPS), and l-arginine (l-Arg) could also elicit the augmentation of intracellular GSH.
Analytical chemistry  •  2019  |  View Paper