Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“Wang et al. demonstrate that IFNγ downregulates both system xc subunits (SLC3A2 and SLC7A11) at the transcriptional level, thereby causing depletion of the intracellular GSH pool and triggering ferroptosis in cancer cells.”
“These results indicate that GSH induces MMP‐2 and MMP‐1 expression in normal HHF and that GSH reduces MMP‐2 and MMP‐1 in transformed fibroblast cells.”
Journal of cellular biochemistry • 1996 | View Paper
“More importantly, the probe revealed that NO induced by interferon-γ (IFN-γ), lipopolysaccharide (LPS), and l-arginine (l-Arg) could also elicit the augmentation of intracellular GSH.”