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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Histamine
Research Papers that Mention the Interaction
“We have measured rate constants for reactions of histamine chloramine with methionine, ascorbate, and GSH at pH 7.4, of 91 M(-1)s(-1), 195 M(-1)s(-1), and 721 M(-1)s(-1), respectively.”
Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione.“Two LA–benzamide HDAC hybrid compounds, UCL M084 and UCL M109 inhibited GPTR contraction after 30 … showed less potent inhibition of agonist-induced contraction than did MGCD0103.ConclusionsThe results showed that GSH … histamine than that induced by 5-HT or carbachol, … and 5-HT than that induced by histamine.”
Effect of antioxidants on airway smooth muscle contraction: action of lipoic acid and some of its novel derivatives on guinea pig tracheal smooth muscle“D-mannitol and reduced glutathione GSH ) modified the kinetics of histamine and LDH release.”
“Preincubation of tracheas with GSH significantly (P < 0.05) suppressed hyperreactivity to histamine as caused by removal of tracheal epithelium.”
“The secretion of histamine was inhibited by anti-free radical interventions such as D-mannitol, reduced glutathione and alpha-tocopherol.”
“Other sulfhydryl agents (alpha-thioglycerol, 2-mercaptoethanol, 2,3-dimercapto-l-propanol, DL-cysteine, glutathione , diethyldithiocarbamate) can similarly modify the effects of histamine on blood pressure but two metal complexing agents (CaNa2 EDTA and orthophenantroline) are inactive.”
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