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“Inhaled LTC4 in conscious guinea pigs treated with S‐hexyl GSH increased both airway resistance and airway hyperinflation.”
“The inhibitory effect of montelukast was diminished by treatment with S‐hexyl GSH , whereas the effect of BayCysLT2RA was enhanced with increasing dose of S‐hexyl GSH.”
European journal of pharmacology • 2017 | View Paper
“In … S‐hexyl GSH (100 μM) the metabolism of [3H]‐LTC4 into [3H]‐LTD4 was inhibited and the LTC4‐induced contractions were resistant to CysLT1 receptor antagonism … by the dual CysLT1/CysLT2 receptor antagonist BAY u9773 (0.3–3 μM) with a pA2‐value of 6.8±0.2.”