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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
Research Papers that Mention the Interaction
“Inhaled LTC4 in conscious guinea pigs treated with S‐hexyl GSH increased both airway resistance and airway hyperinflation.”
“The inhibitory effect of montelukast was diminished by treatment with S‐hexyl GSH , whereas the effect of BayCysLT2RA was enhanced with increasing dose of S‐hexyl GSH.”
CysLT2 receptor activation is involved in LTC4‐induced lung air‐trapping in guinea pigs“In … S‐hexyl GSH (100 μM) the metabolism of [3H]‐LTC4 into [3H]‐LTD4 was inhibited and the LTC4‐induced contractions were resistant to CysLT1 receptor antagonism … by the dual CysLT1/CysLT2 receptor antagonist BAY u9773 (0.3–3 μM) with a pA2‐value of 6.8±0.2.”
“However, S-alkyl glutathiones hexyl and octyl), sulfobromophthalein-glutathione, glutathione monoethyl ester, probenecid (5 mM) and ophthalmic acid (10 mM) inhibited GSH uptake significantly.”
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