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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Halothane
Research Papers that Mention the Interaction
“Following Veh + 1.0% halothane, hepatic glutathione was found to be decreased by 60%.”
A Model for Fatal Halothane Hepatitis in the Guinea Pig“The concentration of reduced glutathione and ascorbic acid was decreased significantly by multiple exposure to halothane in guinea pigs but not in rats.”
“The ability of halothane to diminish hepatic glutathione S-transferase activity in vivo may in part reflect the time-dependent inhibition of glutathione S-transferase isoenzymes containing the 3- and 4-subunits.”
“The role of GSH in the metabolism of halothane , however, is still unclear.”
“Exposure to halothane and to isoflurane, but not to enflurane, further decreased the glutathione level.”
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