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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Haloperidol
Research Papers that Mention the Interaction
“During ferroptosis, haloperidol substantially increased the cellular levels of Fe2+, GSH and lipid peroxidation.”
Haloperidol, a sigma receptor 1 antagonist, promotes ferroptosis in hepatocellular carcinoma cells.“ Haloperidol administration for 2 weeks results in significant reduction in the concentration of GSH in the CSF.”
“ HAL caused significant (p < 0.001) reductions in SOD, CAT, and GSH.”
The role of oxidative stress in ovarian toxicity induced by haloperidol and clozapine—a histological and biochemical study in albino rats“ Haloperidol decreased GSH and TAC and increased MDA and nitrite.”
“ HAL significantly decreased GSH levels and enhanced lipid peroxidation, whereas B1, B12, and vitamin B cocktail prevented the decrease in GSH levels.”
“Biochemical analysis revealed that chronic haloperidol treatment significantly induced lipid peroxidation and decreased the levels of glutathione and of the antioxidant defense enzymes, superoxide dismutase and catalase, in the brains of rats.”
“Biochemical analysis revealed that chronic haloperidol treatment induces lipid peroxidation and decreases the glutathione ( GSH ) levels in the forebrains of rats.”
“Biochemical analysis revealed that chronic haloperidol treatment significantly induced lipid peroxidation, decreased glutathione (GSH), superoxide dismutase (SOD), and catalase levels in the brains of rats.”
“ Haloperidol induced a significant decrease in the glutathione (GSH) content in selected areas of the brain and in the liver.”
“Chronic treatment with haloperidol induced a significant decrease in the cellular glutathione ( GSH ) content in selected areas of the brain (cerebellum, striatum and cortex) and in the liver.”
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