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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Glycyrrhizic Acid
Research Papers that Mention the Interaction
“The levels of LDH, Fe2+, MDA, ROS were decreased, while the level of GSH was increased by GLY treatment.”
Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress“In conclusion, glycyrrhizin increases hepatic glutathione content possibly through inhibition of Mrp2 which then reduces the biliary excretion of glutathione.”
Effects of glycyrrhizin on biliary transport and hepatic levels of glutathione in rats“Treatment with GA significantly increased SOD and GSH levels and decreased myocardial LPO and IP levels.”
“ Glycyrrhizin up to 100 μM significantly attenuated cell death and depletion of GSH due to MPP+ concentration-dependently.”
“However, preincubation of cells with GA resulted in the decrease in free radical production rate and increase in reduced intracellular glutathione level.”
“When rats were given GR 100 mg/kg for 10 days, GR suppressed the elevation of the lipid peroxide level, serum AST, ALT, LDH level, and the decrease in glutathione content during the period of reperfusion.”
“Treatment with various doses of SLN and GLN significantly reduced ALT, AST, ALP, and TBARS levels and increased GSH , SOD, and CAT levels.”
Hepatoprotective Effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in Combination: A Possible Synergy
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