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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Glycylglycine

supplement:

Glutathione

supplement:

Glycylglycine

Research Papers that Mention the Interaction

The γ‐… acceptor glycylglycine , a co‐substrate for γ‐GT, … the growth‐inhibitory effect of GSH , which in contrast was decreased by the γ‐GT inhibitors, serine‐borate complex and acivicin, suggesting that … production of reactive forms of oxygen (probably H2O2) was mediated by cysteinyl‐glycine after GSH hydrolysis.
International journal of cancer  •  1997  |  View Paper
Glutathione loss was markedly accelerated by addition of various amino acids or dipeptides to the medium (e.g. glycylglycine , methionine, cysteine, cystine, and glutamate); this effect was abolished by serineborate, a potent inhibitor of y-glutamyltransferase.
The Journal of biological chemistry  •  1980  |  View Paper
Injection of glycylglycine also decreased glutathione levels, an effect probably mediated by γ-glutamyltranspeptidase.
Biochemical and biophysical research communications  •  1975  |  View Paper
The results showed that the optimum browning inhibitory effect was obtained by adding GSH after Gly-Gly and Ara heating at 80 °C for 60 min.
Journal of agricultural and food chemistry  •  2019  |  View Paper
The addition of Cys or Gly individually enhances the production of GSH.
Applied Biochemistry and Biotechnology  •  2011  |  View Paper