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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Folate

supplement:

Glutathione

supplement:

Folate

Research Papers that Mention the Interaction

Glutathione peroxidase, glutathione and superoxide dismutase significantly increased after the folate treatment; moreover, malonyldialdehyde and von Willebrand factor decreased concomitantly.
European Journal of Clinical Pharmacology  •  2001  |  View Paper
Folate deprivation decreased the reduced form of glutathione , indicating a depletion of oxidative buffering capacity.
Neurobiology of Disease  •  2003  |  View Paper
Therapeutical interventions that aim to increase GSH concentrations in vivo include N-acetyl cysteine; Nrf-2 activation via hyperbaric oxygen therapy; dimethyl fumarate; phytochemicals, including curcumin, resveratrol, and cinnamon; and folate supplementation.
Molecular Neurobiology  •  2014  |  View Paper
These results indicate that diet has an important influence on the toxicity of cyclophosphamide and 5-fluorouracil and that folate status modulates hepatic glutathione levels, which is a major cellular defense against oxidant and alkylating agent damage.
The Journal of laboratory and clinical medicine  •  2002  |  View Paper