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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
supplement:
Epigallocatechin
Research Papers that Mention the Interaction
“In G6PD-deficient cells, GSH was reduced by 43.3% ( EGC at 0.05 mg/ml) and 33.3% (EGCG at 0.5 mg/ml), compared with pre-challenged levels.”
Pro-oxidative effects of tea and polyphenols, epigallocatechin-3-gallate and epigallocatechin, on G6PD-deficient erythrocytes in vitro.“A 4-hr exposure to EGCG lessened the intracellular level of reduced glutathione in the CAL27 and HSG(1) cells, but not in the GN56 fibroblasts.”
“ACS67, ACS1, and the antioxidant epigallocatechin gallate (EGCG) all stimulated GSH levels and significantly attenuated H(2)O(2)-induced toxicity to RGC-5 cells, whereas latanoprost did not.”
ACS67, a hydrogen sulfide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture.“Both Cys and GSH increased the rate of EGCG oxidation at pH 4.”
Oxidative stability of (-)-epigallocatechin gallate in the presence of thiols.“The interaction between EGCG and the key peptides or proteins (e.g. glutathione , enzymes) in vivo is thought to be involved in the toxicity and anti-cancer mechanism of EGCG.”
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