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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Edaravone
Research Papers that Mention the Interaction
“ Edaravone exerted a long-term neuroprotective effects in 6-OHDA-induced PD animal model by attenuating changes in the levels of GSH and MDA in SN, caused by oxidative stress.”
Edaravone Protects Neurons in the Rat Substantia Nigra Against 6-Hydroxydopamine-Induced Oxidative Stress Damage“Combined before-and-after treatment with Ed significantly ameliorated the KA-induced decrease of glutathione and blocked the KA-induced increase of 4-hydroxy-2-nonenal (HNE).”
“One possible explanation is that GSH undergoes intermolecular hydrogen bonding with edaravone anions , while cysteine does not, as it favors intramolecular hydrogen boding.”
Stabilizers of edaravone aqueous solution and their action mechanisms. 2. Glutathione
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