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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutathione and Docosahexaenoic Acid

supplement:

Glutathione

Research Papers that Mention the Interaction

After that, the thiol-ene click reaction was initiated to couple GSH and DHA to deplete intracellular GSH.
Journal of photochemistry and photobiology. B, Biology  •  2020  |  View Paper
We recently showed that DHA upregulates glutathione ( GSH ) content via an induction of its related enzymes γ-glutamylcysteine ligase and glutathione reductase.
British Journal of Nutrition  •  2006  |  View Paper
Investigating the mechanism underlying DHA‐induced apoptosis, we showed that DHA induced a rapid and dramatic (>60%) intracellular depletion of reduced glutathione ( GSH ), without affecting oxidized glutathione (GSSG).
Annals of the New York Academy of Sciences  •  2003  |  View Paper
DHA induced low glutathione levels in RBCs, indicating that oxidative stress may be involved in artemisinin toxicity; effects were extremely rapid, with altered RBCs seen as early as GD10.
Reproductive toxicology  •  2006  |  View Paper
We suggest that DHA plays an important role in inducing an antioxidative defense against active oxygen by enhancing the cerebral activities of CAT, GPx, and GSH.
Journal of neurochemistry  •  1999  |  View Paper
In addition, GSH modulated the cellular redox balance through maintaining increased GSH: GSSG and AsA: DHA ratios, and also increased phytochelatins contents.
Chemosphere  •  2016  |  View Paper