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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
drug:
Dasatinib
Research Papers that Mention the Interaction
“… Dasatinib dramatically increased the level of …, reduced the intracellular glutathione ( GSH ) content, attenuated the activity of superoxide dismutase (SOD), generated malondialdehyde (MDA), a product of lipid peroxidation, decreased the mitochondrial … factor erythroid 2-related factor 2 (Nrf2) and mitogen-activated protein kinases (MAPK) related to oxidative stress and survival.”
Oxidative stress is involved in Dasatinib-induced apoptosis in rat primary hepatocytes.
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