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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glutathione
drug:
Darinaparsin
Research Papers that Mention the Interaction
“Thus, 1mM GSH modulates AS3MT activity, increasing both methylation rates and yield of DMAs(III).”
Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione.“Both MADG and DMAG were unstable in solution when the GSH concentration was lower than 1 mM, and were hydrolyzed and oxidized to MMAV and DMAV, respectively.”
“Intracellular glutathione GSH ) was significantly depleted by As(III) exposure.”
“ascorbic acid (ASC), glutathione GSH ), non-protein thiols (NPTs) and phytochelatins (PCs) biosynthesis involving phytochelatin synthase (PCS) activity increased more significantly during As(III) stress.”
Arsenic accumulation and tolerance in rootless macrophyte Najas indica are mediated through antioxidants, amino acids and phytochelatins.
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