supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Glutathione
drug:
Cupric Chloride
Research Papers that Mention the Interaction
“Incubation of RBC with CuCl2 increased protein oxidation, lipid peroxidation, methemoglobin formation and lowered glutathione content.”
Mitigation of Cu(II)-induced damage in human blood cells by carnosine: An in vitro study.“We found that CuCl2 exposure significantly increased brain oxidative stress as manifested by elevated malondialdehyde levels, decreased reduced glutathione content, and depressed antioxidant enzyme activities in brain tissues when compared with control groups.”
Alleviative effect of licorice on copper chloride-induced oxidative stress in the brain: biochemical, histopathological, immunohistochemical, and genotoxic study“This effect was strongly enhanced by CuCl2 and suppressed by EDTA, bathocuproinedisulfonic acid disodium salt, methionine, glutathione reduced form or catalase, but was not affected by mannitol, sodium benzoate or sodium azide.”
“At 24 hours of CuCl2 intervention, intracellular reduced glutathione level and glutathion reductase activity were significantly decreased in the 100 μmol/L CuCl2 group compared to the control group.”
Oxidative damage of copper chloride overload to the cultured rat astrocytes.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback