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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Brostallicin

supplement:

Glutathione

Research Papers that Mention the Interaction

A peculiarity of brostallicin is its in vitro reactivity in the DNA alkylation assays only in the presence of glutathione.
Moreover, due to its interaction with glutathione, brostallicin may have a role for the tailored treatment of tumors characterized by constitutive or therapy-induced overexpression of glutathione/glutathione-S-tranferase levels.
Journal of medicinal chemistry  •  2004  |  View Paper
The cytotoxic activity of Brostallicin was previously shown to be enhanced in the presence of high glutathione and glutathione transferase levels.
Cancer letters  •  2006  |  View Paper