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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Benzyl Isothiocyanate
Research Papers that Mention the Interaction
“ BITC upregulated the expression of HO-1, GSTP, and GCLM mRNA and protein as well as GSH contents, which suppressed oxidative damage.”
Benzyl Isothiocyanate Ameliorates High-Fat Diet-Induced Hyperglycemia by Enhancing Nrf2-Dependent Antioxidant Defense-Mediated IRS-1/AKT/TBC1D1 Signaling and GLUT4 Expression in Skeletal Muscle.“ BITC also decreased expression of specificity proteins (Sp) Sp1, Sp3, and Sp4 transcription factors (TFs) and several pro-oncogenic Sp-regulated genes, including STAT3 and phospho-STAT3 (pSTAT3), and GSH attenuated these responses.”
“ BITC effectively decreased the intracellular GSH and GSH/GSSG ratio and redox balance recovery by thiol-containing redox compounds, but not by free radical scavengers.”
“p-Methoxyphenol, benzyl isothiocyanate , coumarin, and 2-tert-butyl-4-hydroxyanisole increased glutathione S-transferase activity of the esophagus by 68 to 135%, alpha-angelicalactone was less effective, and 3-tert-butyl-4-hydroxyanisole had only a small enhancing capacity.”
Enhancement of glutathione S-transferase activity of the esophagus by phenols, lactones, and benzyl isothiocyanate.
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