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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Glutathione and Benzyl Isothiocyanate



Research Papers that Mention the Interaction

BITC also decreased expression of specificity proteins (Sp) Sp1, Sp3, and Sp4 transcription factors (TFs) and several pro-oncogenic Sp-regulated genes, including STAT3 and phospho-STAT3 (pSTAT3), and GSH attenuated these responses.
The Journal of Biological Chemistry  •  2016  |  View Paper
BITC effectively decreased the intracellular GSH and GSH/GSSG ratio and redox balance recovery by thiol-containing redox compounds, but not by free radical scavengers.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2016  |  View Paper
p-Methoxyphenol, benzyl isothiocyanate , coumarin, and 2-tert-butyl-4-hydroxyanisole increased glutathione S-transferase activity of the esophagus by 68 to 135%, alpha-angelicalactone was less effective, and 3-tert-butyl-4-hydroxyanisole had only a small enhancing capacity.
Cancer research  •  1982  |  View Paper
BITC upregulated the expression of HO-1, GSTP, and GCLM mRNA and protein as well as GSH contents, which suppressed oxidative damage.
Journal of agricultural and food chemistry  •  2020  |  View Paper