Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Glutathione and Aurothioglucose

Research Papers that Mention the Interaction

GSH depletion completely prevented the protective effects of ATG in LPS/hyperoxia-exposed mice.
Using a murine ARDS model, we tested the hypothesis that aurothioglucose (ATG) treatment increases pulmonary GSH levels, attenuates lung injury, and decreases mortality in a GSH-dependent manner.
Antioxidants & redox signaling  •  2014  |  View Paper
ATG inhibited, in addition to the classifical selenium-dependent glutathione peroxidase, both cytosolic and microsomal (basal and N-ethyl maleimide-stimulated) glutathione S-transferase activities with greater than 80% inhibition achieved at 100 μM ATG.
Lipids  •  1988  |  View Paper
The seven-day treatment with ATG significantly increased glutathione levels in kidney but not in liver or plasma.
Agents and Actions  •  1988  |  View Paper