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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
drug:
Aspartate
Research Papers that Mention the Interaction
“ Aspartate or glutamate pretreatment also increased the levels of glutathione and mitochondrial ATP while decreased the level of lipid peroxides in the cardiac tissue.”
Aspartate and glutamate prevents isoproterenol-induced cardiac toxicity by alleviating oxidative stress in rats.“The order of antagonistic … to the response to L‐aspartate …: gamma‐DGG (69%) greater than APV (66%) greater than NMDLA (60%) greater than GDEE (31%), and that to the response to L‐glutamate was: GDEE (63%) greater than NMDLA (22%) greater than gamma‐GDD (15%) greater than APV (14%).”
“Large loads of aspartate cause 20% diminution of glutathione in outer cortex, due entirely to changes in proximal tubule segments.”
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