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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutathione and Alpha-Tocopherol Succinate

Research Papers that Mention the Interaction

VES also induced a concentration-dependent generation of reactive oxygen species (ROS) and a concentration-dependent depletion of glutathione (GSH) in the cells.
Medical science monitor : international medical journal of experimental and clinical research  •  2010  |  View Paper
We report here that alpha-tocopheryl succinate (TOS), a vitamin E analogue, decreased intracellular GSH concentration and blocked MRP1 function in glioblastoma cells.
Cancer letters  •  2005  |  View Paper
GSH disappeared when … presence of alpha-tocopheryl succinate (TS) pretreatment, it was noted that bleb formation, expressed as the percentage of cells bearing blebs, the average bleb size, or … concentration was 2.0 mM. TBH-induced thiobarbituric acid reactive substances and LDH leakage were completely abolished by TS pretreatment.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2000  |  View Paper
In vitro drug release results revealed that more TOS and curcumin were released in the presence of GSH (5 mM) than the physiological pH value.
Pharmaceutics  •  2020  |  View Paper