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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Possible Interaction: Glutathione and 3-((6-Deoxymannopyranosyl)Oxy)-7-(Glucopyranosyloxy)-5-Hydroxy-2-(4-Methoxyphenyl)-8-(3-Methyl-2-Butenyl)-4H-1-Benzopyran-4-One
Research Papers that Mention the Interaction
“Additionally, ICA exhibited strong antitumor activity, as evidenced by reductions in cell migration, adhesion, and intracellular glutathione ( GSH ) levels and by increases in the EC109 and TE1 cell apoptotic index, Caspase 9 activity, reactive oxygen species (ROS) level, and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity.”
Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling“Additionally, ICA exhibited potent anticancer activity, as evidenced by reductions in A549 cell adhesion, migration and intracellular glutathione ( GSH ) levels and increases in the apoptotic index, Caspase 3 activity, and reactive oxygen species.”
“ Icariin increased the GPx and GSH levels which are responsible from scavenging hydroxyl radical and hydrogen peroxide.”
Icariin promotes early and late stages of fracture healing in rats.“… ICA pretreatment markedly reduced intestinal I/R-induced ALI as indicated by histological alterations, including decreased tumor necrosis factor-α (… oxidative stress, acetylated FOXO3 and B-cell lymphoma 2 (Bcl-2)-interacting mediator of cell death levels, and increased glutathione (GSH), GSH peroxidase, SIRT1, manganese … in rat lung tissues.”
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